Description
About the Brand of the Drug:
Duratia 60 mg is a renowned pharmaceutical product developed by Fortune Healthcare India, is marketed as Priligy in the United States. This medication falls under the classification of Schedule H drugs, necessitating a prescription for its purchase. Duratia’s key ingredient is Dapoxetine; a potent compound specifically formulated to address premature ejaculation in adult males aged 18 to 64.
About the Drug:
Duratia is available in 60 mg dosage strength, with Dapoxetine serving as its active pharmaceutical ingredient. Dapoxetine, belonging to the selective serotonin reuptake inhibitor (SSRI) class, has proven effective in numerous male patients grappling with premature ejaculation. Each strip of Duratia contains 10 orally administered tablets. In the USA, a pack of 60 tablets generally costs around $57 and can be conveniently obtained from reputable online pharmacies.
About the Salt of the Drug Duratia 60 mg:
Dapoxetine, as previously mentioned, is a compound primarily employed to combat premature ejaculation in adult males. Initially developed by Eli Lilly Pharmaceuticals, it was subsequently acquired by Johnson & Johnson. Dapoxetine, classified as an SSRI, shares its roots with medications commonly prescribed for depression. Notably, Dapoxetine’s capacity to boost serotonin levels in the brain enhances ejaculatory control, thereby benefiting one’s sexual well-being.
Mechanism of Action:
Belonging to the SSRI family, which is widely employed for depression treatment, Dapoxetine operates by inhibiting the breakdown and reuptake of serotonin in the brain. By binding to the receptors responsible for serotonin reabsorption, Dapoxetine raises serotonin levels, which subsequently bind to their designated 5-HT receptors. This heightened binding of serotonin to its receptors effectively delays ejaculation in men. The maximum effect of Dapoxetine is typically achieved within 1.01 hours and 1.27 hours for doses of 30 mg and 60 mg, respectively. In the presence of high-fat meals, the time required to reach maximum effectiveness extends to approximately 1.83 hours.
Note: Although Dapoxetine has received a “not-approvable” letter from the US Food and Drug Administration (USFDA) and is not approved for sale in the USA, it is currently undergoing phase 3 clinical trials. Nevertheless, Dapoxetine has been approved and launched in several countries, including Sweden, Finland, Austria, Portugal, Germany, Italy, Spain, Mexico, South Korea, and New Zealand in 2009/2010. While approved in Australia, it has yet to be made available on the market.
Onset and Duration of Action:
Typically, the effect of Duratia 60 mg can be observed within 1-3 hours after administration, with a duration of action lasting approximately 1-2 hours.
Medical Uses of the Duratia 60 mg:
Duratia 60 tablet is primarily prescribed for the following medical conditions:
Premature Ejaculation: Premature ejaculation, a common male sexual problem characterized by achieving climax earlier than desired, can be addressed with Duratia. It is worth noting that while Duratia is not approved for use in the USA, it is being illicitly utilized there. Premature ejaculation can be either physiological or biological in nature, and Duratia offers assistance in overcoming this issue.
Antidepressant: Due to its classification as an SSRI, Dapoxetine can also serve as an antidepressant, aligning with the drugs commonly employed for depression treatment.
Side Effects:
Some potential side effects associated with Duratia (Dapoxetine) may include:
- Dizziness and lightheadedness
- Nervousness and confusion
- Excessive sweating
- Headache
- Diarrhea
- Sleeplessness
- Decreased libido
- Blurred vision
- Ringing or buzzing in the ears
- Fast/irregular heartbeat (severe)
- Increase in blood pressure
- Excessive tiredness
- Dry mouth
In the event of experiencing severe side effects, it is crucial to promptly contact your doctor and discontinue the use of the medication until further guidance is provided. It is important to note that the list of side effects provided is not exhaustive and only includes those observed thus far. Each individual may have a unique reaction to the drug, and if any unfamiliar or concerning side effects arise, it is essential to consult your doctor as soon as possible.
Proper Usage Instructions:
Please be aware that Duratia is currently not approved for consumption or purchase in the United States, as it is still undergoing evaluation by the regulatory authorities. However, in countries where it has been approved, Duratia is strictly prescribed by doctors and can only be obtained with a genuine prescription. Self-medication should be avoided at all costs, and it is vital to adhere to the instructions provided in the prescription for safe and effective results.
For optimal outcomes, it is recommended to take Duratia approximately one hour before anticipated sexual activity. The tablet should be swallowed with a large glass of water, with or without food. To ensure the drug reaches its maximum effect within the desired timeframe, it is advisable to avoid consuming large meals alongside the medication.
Missed Dose Guidelines:
Since Duratia is taken on an as-needed basis, specifically one hour before sexual activity, the likelihood of missing a dose is relatively low. However, if a dose is missed, it is important not to increase the dosage the next time. Simply continue with the prescribed regimen without doubling the dose.
Overdose Precautions:
Taking an overdose of Duratia can lead to the aforementioned severe side effects. If any of these symptoms manifest, it is crucial to promptly call or visit your doctor for immediate medical attention.
Drugs Known to Interact:
Duratia is contraindicated with certain medications due to potential interactions. These include:
- Erythromycin (moderate)
- Fluconazole (moderate)
- Ketoconazole (severe)
- Lithium (severe)
- Tramadol (severe)
- Warfarin (minor)
- Ritonavir (severe)
- Verapamil (moderate)
Instances When the Drug should be Avoided:
Duratia is not recommended under the following circumstances:
Allergy: Individuals who are allergic to dapoxetine or any other components present in the medication should avoid its use.
Heart Failure: Patients with a history of heart failure should refrain from using this medicine, as it may worsen their condition.
Heart Rhythm Disorders: Individuals with heart rhythm disorders are at an increased risk and should avoid using this medication.
Bipolar Disorder: Duratia is not recommended for patients with a history of mania or severe depression associated with bipolar disorder.
Loss of Consciousness: Individuals who experience frequent episodes of loss of consciousness and muscle strength should refrain from using this medicine.
Kidney Disease: Use of this medication increases the risk of kidney failure and should be avoided in patients with kidney disease.
Liver Disease: Patients with liver disease should exercise caution when considering the use of Duratia.
Monoamine Oxidase Inhibitors (MAOIs): Duratia should not be used concurrently with medications belonging to the Monoamine oxidase inhibitors (MAOIs) class. It is advisable to wait for 14 days after discontinuing MAOI treatment before starting Dapoxetine. Similarly, MAOI medication can be taken 7 days after ceasing the use of Dapoxetine.
Thioridazine: It is recommended to wait for 14 days after discontinuing thioridazine treatment before taking Dapoxetine. Similarly, thioridazine can be taken 7 days after stopping the use of Dapoxetine
Precautions and Avoidances:
In addition to the aforementioned drug interactions, it is important to avoid consuming alcohol while taking Duratia. Alcohol consumption can intensify dizziness and should be strictly avoided to ensure the safe and effective use of the medication.
General Information and Safety Measures:
It is strongly advised not to engage in driving while under the influence of Duratia, as it may cause dizziness and headaches, posing a risk of accidents. Therefore, exercising caution and refraining from driving during the medication’s effect is essential.
Pregnancy and Lactation:
Duratia is not recommended for use in women who are pregnant or breastfeeding. It is crucial to consult with a healthcare professional for alternative options and appropriate guidance during these stages.
Storage Recommendations:
To maintain the quality and effectiveness of Duratia tablets, they should be stored at temperatures below 36°C.
Frequently Asked Questions (FAQs) about Duratia:
Q: Can women use this medicine?
A: No, this medicine is not recommended for use in women. It is specifically formulated for male individuals.
Q: How long does it take for the medicine to show its effect?
A: The onset of Duratia’s effect typically occurs within 1-3 hours after ingestion. However, individual responses may vary.
Q: Can I purchase this medicine without a prescription?
A: No, you cannot purchase Duratia without a valid prescription. It is crucial to consult a healthcare professional for appropriate medical assessment and obtain a prescription to ensure safe usage. Self-medication is strongly discouraged due to potential risks to your health and well-being.
Disclaimer: The content of this page is for informational purposes and is not intended to replace medical advice, diagnosis, or treatment in any way. If you have any questions regarding a medical condition, please consult your doctor or seek help from a qualified healthcare provider before self-medicating. If you have any concerns about the content of our website, please contact us at support@sexmedz.com.
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